Bakuchiol

A plant-derived active that works on the look of fine lines and wrinkles, with a gentle feel that suits skin which finds retinol uncomfortable.

Last reviewed August 8, 2026 · 29 sources, 6 of them regulators or official bodies · how we check this

Best time
Morning or evening
How often
Daily
Strength
Gentle
Sun sensitivity
None

Where to apply

All over the face

Never in your eyes or on your lips.

What does Bakuchiol do?#

Bakuchiol is a plant-derived active that helps improve the appearance of fine lines and wrinkles in a similar way to retinol, but with a gentler profile. It is a popular alternative for those who find retinol too irritating or are looking for a botanical option.

  • Helps reduce the visible appearance of fine lines and wrinkles
  • Supports a smoother, firmer-looking complexion
  • Generally well-tolerated with a gentle feel on the skin

How it works

Bakuchiol is a plant-based ingredient sourced from the Psoralea corylifolia seed. It has gained popularity as a gentler botanical alternative to retinol. With consistent use, it helps contribute to a smoother, firmer-looking appearance. It also provides antioxidant support for skin that looks healthy and radiant despite everyday environmental stress.

How to use Bakuchiol#

  • Morning or evening, whichever suits you — it stays stable in daylight, so it does not have to be an evening-only step.
  • On clean skin, before your moisturizer.
  • Every day from the start. There is no easing-in period and no reason to build up slowly.
  • Spread it over the whole face rather than dabbing it on particular spots.
  • Patch test on your inner arm before the first use. Contact allergy to bakuchiol is uncommon, but it has been reported.
  • Expect it to feel unremarkable. There is no settling-in phase, no flaking stage and no early breakout to ride out.
  • A daily sunscreen goes with anything you use for fine lines and uneven tone — not because this one makes skin burn, but because sun undoes the work.
  • If you get itchy redness or a rash that spreads rather than settles, stop and see a doctor. That is different from a brief tingle on the first application.
  • Bakuchiol concentration and purity can vary between products — look for products that specify bakuchiol percentage on the label.

Discontinue use if persistent irritation occurs.

The form you will see it in

Bakuchiol serum

Where it goes
Before moisturizer

Using Bakuchiol with other ingredients

Pairs well with Bakuchiol

Niacinamide

Works well together

Both support a smoother, more even-looking complexion in complementary ways.

Hyaluronic acid

Works well together

Hyaluronic acid adds hydration to complement bakuchiol's smoothing benefits.

What not to use with Bakuchiol

Nothing flagged. None of the ingredients this wiki covers needs to be kept apart from Bakuchiol — check the label of anything not covered here.

Who should avoid Bakuchiol?#

Six situations change whether Bakuchiol suits your skin right now. Each one is either a reason to skip it, a reason to go slowly, or nothing to watch for.

Maternity & Nursing
Go slowly
Fragile or Sensitive
Go slowly
Recent Facial or Laser
Go slowly
Prone to Redness
Go slowly
Dry or Itchy Patches
Go slowly
Recent Shave or Wax
No caution

Maternity & NursingIf you are pregnant or nursing, you may prefer to check with your healthcare provider before use.

Fragile or SensitiveUse it less often — or stop — if it feels uncomfortable, and keep it off skin that’s broken, cut or sunburned.

Recent Facial or LaserWait until your skin feels settled before reintroducing — typically 7 to 14 days after a facial or laser appointment.

Prone to RednessTry it on a small area first, and use it less often — or stop — if you notice stinging or extra redness.

Dry or Itchy PatchesKeep the rest of your routine well moisturized, and use it less often — or stop — if you notice tightness or itching.

Cosmetic strength limits for Bakuchiol where you live#

RegionMaximum strength
United StatesNo explicit cap
CanadaNo explicit cap
European UnionNo explicit cap
Great BritainNo explicit cap

No cosmetic regulator in these four markets sets a maximum strength for bakuchiol. That is a limit on the rules, not a signal to use more: how much goes into a product is the formulator's decision.

Products with Bakuchiol#

Common questions about Bakuchiol#

When should you apply Bakuchiol?

Morning or evening, whichever suits you — it stays stable in daylight, so it does not have to be an evening-only step.

How often can you use Bakuchiol?

Daily.

Where do you apply Bakuchiol?

All over the face. Keep it away from your eyes and lips.

Does Bakuchiol make skin more sensitive to the sun?

No. Bakuchiol is not flagged as increasing sun sensitivity.

What should you not use with Bakuchiol?

Nothing flagged. None of the ingredients this wiki covers needs to be kept apart from Bakuchiol — check the label of anything not covered here.

Who should avoid Bakuchiol?

Go slowly with Maternity & Nursing, Fragile or Sensitive, Recent Facial or Laser, Prone to Redness and Dry or Itchy Patches.

Is there a cosmetic limit for Bakuchiol?

No. No cosmetic regulator in the United States, Canada, the European Union or Great Britain sets a maximum strength for it. That is a limit on the rules, not a signal to use more.

How we check this#

Everything on this page traces to the sources listed below — regulators' own publications and published studies. Where the evidence does not answer a question, it is left unanswered.

Some sources below are the official product information for prescription medicines — some contain this ingredient at higher strengths, others are cited for how they interact with it. We use them for their safety and handling detail only. A cosmetic product is not one of those medicines and is not intended to treat any condition.

Our review is AI-assisted and is not a named expert's opinion. Last reviewed August 8, 2026.

Think something here is out of date or wrong? Email us at wiki@skinintelligence.ai with your reasoning and where you read it. We read what people send, and we update the page when the sources support it.

Regulators and official bodies · 6

  1. S23Regulation (EC) No 1223/2009 on cosmetic products, Annex II (list of substances prohibited in cosmetic products), entry 358 (furocoumarins), entry 34 (imperatorin), entry 35 (Ammi majus L.). Retained EU law as published at legislation.gov.uk — applies to both EU and UK.
  2. S24Regulation (EC) No 1223/2009 on cosmetic products, Annex III (restricted substances). No bakuchiol, Psoralea or furocoumarin entry. legislation.gov.uk.
  3. S25Health Canada, Cosmetic Ingredient Hotlist: Prohibited and Restricted Ingredients — "Furocoumarins, except for naturally occurring in plant extracts", CAS 66-97-7, sun tanning products, 1 mg/kg (1 ppm).
  4. S26US FDA, Prohibited & Restricted Ingredients in Cosmetics — no entry for bakuchiol, furocoumarins, psoralens or Psoralea.
  5. S27Roaccutane 10 mg soft capsules, Summary of Product Characteristics, §4.3, §4.4, §4.5, §4.6 (emc product 100633). Evidence about isotretinoin, not about bakuchiol.
  6. S28Differin Gel 0.1% w/w, Summary of Product Characteristics, §4.3, §4.4, §4.5, §4.6 (emc product 921). Evidence about adapalene, not about bakuchiol.

Studies and references · 23

  1. S1Dhaliwal S, Rybak I, Ellis SR, Notay M, Trivedi M, Burney W, Vaughn AR, Nguyen M, Reiter P, Bosanac S, Yan H, Foolad N, Sivamani RK. Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing. Br J Dermatol 2019;180(2):289–296. PMID 29947134. DOI 10.1111/bjd.16918.
  2. S2Chaudhuri RK, Bojanowski K. Bakuchiol: a retinol-like functional compound revealed by gene expression profiling and clinically proven to have anti-aging effects. Int J Cosmet Sci 2014;36(3):221–230. PMID 24471735.
  3. S3Draelos ZD, Gunt H, Zeichner J, Levy S. Clinical Evaluation of a Nature-Based Bakuchiol Anti-Aging Moisturizer for Sensitive Skin. J Drugs Dermatol 2020;19(12):1181–1183. PMID 33346506. DOI 10.36849/JDD.2020.5522.
  4. S4Bluemke A, Ring AP, Immeyer J, Hoff A, Eisenberg T, Gerwat W, Meyer F, Breitkreutz S, Klinger LM, Brandner JM, Sandig G, Seifert M, Segger D, Rippke F, Schweiger D. Multidirectional activity of bakuchiol against cellular mechanisms of facial ageing. Int J Cosmet Sci 2022;44:377–393. PMID 35514037.
  5. S5Brownell L, Geen S, E Y, Lee WL. A Clinical Study Evaluating the Efficacy of Topical Bakuchiol (UP256) Cream on Facial Acne. J Drugs Dermatol 2021;20(3):307–310. PMID 33683079.
  6. S6Poláková K, Fauger A, Sayag M, Jourdan E. A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris. Clin Cosmet Investig Dermatol 2015;8:187–191. PMID 25914553.
  7. S7Puyana C, Chandan N, Tsoukas M. Applications of bakuchiol in dermatology: Systematic review of the literature. J Cosmet Dermatol 2022;21(12):6636–6643. PMID 36176207.
  8. S8Fanning JE, McGee SA, Ibrahim OI. Human Clinical Trials Using Topical Bakuchiol Formulations for the Treatment of Skin Disorders: A Systematic Review. J Drugs Dermatol 2024;23(4):239–243. PMID 38564402.
  9. S9Mota S, Rosa GP, Barreto MC, Garrido J, Sousa E, Cruz MT, Almeida IF, Quintas C. Comparative Studies on the Photoreactivity, Efficacy, and Safety of Depigmenting Agents. Pharmaceuticals (Basel) 2023;17:55. PMID 38256889 · PMC10820089.
  10. S10Alalaiwe A, Hung CF, Leu YL, Tahara K, Chen HH, Hu KY, Fang JY. The active compounds derived from Psoralea corylifolia for photochemotherapy against psoriasis-like lesions. Eur J Pharm Sci 2018;124:114–126. PMID 30153523.
  11. S11Jeong M, Hong T, Lee K, Hwangbo H, Kim M, Ma W, Zahn M. HPLC Method for Simultaneous Quantification of Bakuchiol and Minor Furocoumarins in Bakuchiol Extract from Psoralea corylifolia. J AOAC Int 2015;98(4):902–906. PMID 26268970.
  12. S12Xu M, Tian XY, Leung KS, Lee KC, Chow TC, Deng B, Yiu CM, Chow CI, Zhao ZZ, Yang ZJ, Fun FW, Xiao TT, Xu W, Deng PX. Embryotoxicity of Psoralea corylifolia L.: in vivo and in vitro studies. Birth Defects Res B Dev Reprod Toxicol 2012;95(6):386–394. PMID 23169613.
  13. S13Shen X, Wang R, He J, Wang N, Zhang W, Zhou L, Li C, Zeng Y, Ao T, Deng H, Zhou K, Shen P, Gao Y, Zhou W. Reproductive toxicity of Fructus Psoraleae in zebrafish: material basis and implications for clinical safety dosing. Phytomedicine 2026;155:158194. PMID 41999703.
  14. S14Malinauskiene L, Linauskiene K, Černiauskas K, Chomičiene A. Bakuchiol — A new allergen in cosmetics. Contact Dermatitis 2019;80(6):398–399. PMID 30644106.
  15. S15Raison-Peyron N, Dereure O. A new case of contact dermatitis to bakuchiol in a cosmetic cream. Contact Dermatitis 2020;82:61–62. PMID 31423588.
  16. S16Sánchez-Arjona M, Rosell-Díaz ÁM, Castaño-Fernández JL, Elosua-González M. Allergic Contact Dermatitis to Bakuchiol Used for Photodamage Prevention: A Case Report. Contact Dermatitis 2026;95(2):229–230. PMID 42014129.
  17. S17Shi X, Wang Y, Zhang H, Zhang T. Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population. Health Sci Rep 2025;8:e71629. PMID 41424674.
  18. S18Brown A, Furmanczyk M, Ramos D, Ribes A, Pons L, Bustos J, de Henestrosa ARF, Granger C, Jourdan E. Natural Retinol Analogs Potentiate the Effects of Retinal on Aged and Photodamaged Skin. Dermatol Ther (Heidelb) 2023;13:2299–2317. PMID 37615835.
  19. S19Nizam NN, Mahmud S, Ark SMA, Kamruzzaman M, Hasan MK. Bakuchiol, a natural constituent and its pharmacological benefits. F1000Res 2023;12:29. PMID 38021404 · PMC10683784.
  20. S20Grzelecka M, Siudem P, Tyburc N, Triyasmono L, Holzgrabe U, Paradowska K. Comparison of Quantification Using UV-Vis, NMR, and HPLC Methods of Retinol-Like Bakuchiol Present in Cosmetic Products. Int J Mol Sci 2025;26:6638. PMID 40724887 · PMC12295351.
  21. S21Kurpet K, Chwatko G. Development of a new chromatographic method for the determination of bakuchiol in cosmetic products. Sci Rep 2023;13:13893. PMID 37620384.
  22. S22Chaudhuri RK. Bakuchiol: From structural mimicry to systems-level skin biology. Int J Cosmet Sci 2026 (online ahead of print). PMID 42332430. DOI 10.1111/ics.70116.
  23. S29ClinicalTrials.gov NCT03112863, "Comparison of the Cosmetic Effects of Bakuchiol and Retinol" — registry record for [1]; 44 actual enrolment; arms "Bakuchiol 0.5% applied to face twice daily" and "0.5% retinol applied to face nightly"; exclusions include pregnant or breastfeeding women, acne, eczema, seborrhoeic dermatitis, rosacea, isotretinoin within 6 months, topical retinoids or antibiotics within 30 days, and chemical peels, laser or injectables within 3 months.

Cosmetic guidance only. Skin Intelligence is a cosmetic skincare tool, not a medical device, and does not diagnose, treat, cure, or prevent any condition. Always follow the directions on the product you are using — where they differ from anything on this page, the label takes precedence. If you have a skin concern, please see a healthcare professional.

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