Zinc Oxide

A fine white mineral that stays on the surface of the skin rather than sinking in, leaving a soft, slightly opaque, matte finish.

On a label you may see
Non-nano zinc oxide and CI 77947

Last reviewed September 1, 2026 · 52 sources, 21 of them regulators or official bodies · how we check this

Best time
Morning
How often
Daily
Strength
Gentle
Sun sensitivity
None

Where to apply

All over the face

Never in your eyes or on your lips.

What does Zinc Oxide do?#

A mineral cream with zinc oxide that sits on the surface of the skin and leaves a soft, slightly opaque, matte finish.

Benefits

  • Leaves a soft matte finish that keeps skin looking less shiny
  • Sits on the surface rather than sinking in, so the finish stays where you put it
  • A gentle texture that suits skin that is easily bothered
  • Comfortable enough for everyday use

How it works

Zinc oxide is a fine mineral powder that does not dissolve into the base it is blended with. It stays as countless tiny particles resting on the skin's surface, and that surface layer is what gives the finish its soft, slightly opaque, matte character.

How to use Zinc Oxide#

  • Before you start

    Expect a pale cast as you apply it. It is the mineral itself, not the formula going wrong.

  • Where it goes

    A cream carrying zinc oxide takes the moisturiser's own place in the morning. Because it sits on the surface rather than sinking in, nothing else goes on top of it.

  • Where to apply

    All over the face. Keep it off broken or irritated skin, keep it out of your eyes, and rinse with water if it gets in.

  • How to apply

    Massage it in fully and give it a minute to settle — it sits on the surface, so it needs a moment to even out.

  • Alongside others

    It layers over everything else without argument — nothing in a normal routine needs to be scheduled around it.

  • What to look for

    The cast is most noticeable on deeper skin tones — a tinted or shade-matched version is the usual fix.

  • If it doesn't suit

    A heavier, more occlusive feel is the common complaint. A lighter formula in the same mineral family is the answer, not a lower amount.

Discontinue use if unexpected discomfort occurs.

The form you will see it in

Zinc oxide mineral cream

Where it goes
As your moisturizer

Using Zinc Oxide with other ingredients

Pairs well with Zinc Oxide

Hyaluronic Acid

Works well together

A hydrating layer underneath keeps skin comfortable under a mineral texture.

Glycerin

Works well together

Long-standing partners in the same mineral formulas.

What not to use with Zinc Oxide

Nothing flagged. None of the ingredients this wiki covers needs to be kept apart from Zinc Oxide — check the label of anything not covered here.

Who should avoid Zinc Oxide?#

Six situations change whether Zinc Oxide suits your skin right now. Each one is either a reason to skip it, a reason to go slowly, or nothing to watch for.

Fragile or Sensitive
Skip it
Maternity & Nursing
No caution
Recent Facial or Laser
No caution
Prone to Redness
No caution
Dry or Itchy Patches
No caution
Recent Shave or Wax
No caution

Cosmetic strength limits for Zinc Oxide where you live#

RegionMost a cosmetic may contain

Where a figure appears, that is the maximum strength allowed or advised for zinc oxide in that market — some are set in cosmetics regulation, others are the ceiling a cosmetic safety panel recommends. Where no figure appears, the market either sets no cosmetic maximum or handles this ingredient outside its cosmetic rules. These are limits, not targets — the right strength for a formula is the formulator's decision.

Open a market to see the rulebook its figure comes from. Those notes describe each market's own rules as we read them, current to August 24, 2026; the linked documents are the authority, and nothing here is legal advice.

Common questions about Zinc Oxide#

When should you apply Zinc Oxide?

Morning.

How often can you use Zinc Oxide?

Daily.

Where do you apply Zinc Oxide?

All over the face. Keep it away from your eyes and lips.

Does Zinc Oxide make skin more sensitive to the sun?

No. Zinc Oxide is not flagged as increasing sun sensitivity.

What should you not use with Zinc Oxide?

Nothing flagged. None of the ingredients this wiki covers needs to be kept apart from Zinc Oxide — check the label of anything not covered here.

Who should avoid Zinc Oxide?

Skip it if any of these apply: Fragile or Sensitive.

Is there a cosmetic limit for Zinc Oxide?

Only some regions set one. The maximum strength for Zinc Oxide in a cosmetic is 25% (sum of nano and non-nano) in the European Union and 25% (sum of nano and non-nano) in Great Britain. No maximum is set in the United States and Canada. A cap is a limit on the rules, not a signal to use more.

How we check this#

Everything on this page traces to the sources listed below — regulators' own publications and published studies. Where the evidence does not answer a question, it is left unanswered.

Some sources below are medical studies. This ingredient has been studied in conditions a doctor treats, and the record cited here includes findings that did not favour it. We use those studies for their safety and handling detail only. A cosmetic product is not a medicine and is not intended to treat, cure or prevent any condition.

Some sources below are the official product information for prescription medicines — some contain this ingredient at higher strengths, others are cited for how they interact with it. We use them for their safety and handling detail only. A cosmetic product is not one of those medicines and is not intended to treat any condition.

Our review is AI-assisted and is not a named expert's opinion. Last reviewed September 1, 2026.

Think something here is out of date or wrong? Email us at wiki@skinintelligence.ai with your reasoning and where you read it. We read what people send, and we update the page when the sources support it.

Regulators and official bodies · 21

  1. S1FDA, Over-the-Counter Monograph M020: Sunscreen Drug Products for Over-the-Counter Human Use (deemed final order, 24 Sep 2021) — §§M020.10(p), M020.20(a), M020.50.
  2. S221 CFR 347.10 — Skin protectant active ingredients (eCFR, title 21 current to 22 Apr 2026).
  3. S3Commission Regulation (EU) 2016/621 of 21 Apr 2016, recitals 1–5 (SCCP 2003, SCCP clarifications, SCCS 18 Sep 2012 opinion + 23 Jul 2013 addendum + 23 Sep 2014 spray opinion).
  4. S4Health Canada, Primary Sunscreen Monograph (Health Products and Food Branch, version 2026-02-27).
  5. S5Sudocrem Antiseptic Healing Cream SmPC (zinc oxide 15.29% w/w), PL 00289/2299, rev. 04/04/2023, emc.
  6. S6Zinc and Castor Oil Ointment BP SmPC (zinc oxide 7.5% w/w), PL 12965/0038, rev. 24/09/2019, emc.
  7. S7Roaccutane 10 mg soft capsules (isotretinoin) — SmPC §4.4.
  8. S8Differin Cream SmPC (adapalene 0.1%), emc.
  9. S9Efracea 40 mg Modified Release Hard Capsules (doxycycline) — SmPC §4.4, §4.5.
  10. S10SCCNFP/0799/04, Updated position paper concerning consumer safety of alpha-hydroxy acids.
  11. S24FDA OTC Monograph M016, Skin Protectant Drug Products for Over-the-Counter Human Use, 24 Sep 2021.
  12. S2521 CFR 73.2991 — Zinc oxide (colour additive exempt from certification), 42 FR 37538 (eCFR) — newly fetched.
  13. S26Regulation (EC) No 1223/2009, consolidated 01.05.2026 — Annex VI Nos 30 & 30a; Annex IV No 144.
  14. S27Assimilated Regulation (EC) No 1223/2009 as it applies in GB, Annexes IV & VI; EUR 2016/621 Annex — legislation.gov.uk.
  15. S28Health Canada, Medicated Skin Care Products Monograph (NHPID).
  16. S29Health Canada, Cosmetic Ingredient Hotlist — zinc oxide absent (checked in full, fetched 2026-09-01).
  17. S39National Rosacea Society, Rosacea Review Spring 2023 — "Prescription and OTC Products Can Work Together to Repair Skin Barrier Damage".
  18. S43Aklief 50 microgram/g cream (trifarotene) — SmPC §4.4, §4.5.
  19. S44Tetralysal 300 mg Hard Capsules (lymecycline) — SmPC §4.4.
  20. S45Methotrexate 2.5 mg Tablets BP — SmPC §4.4.
  21. S46Deximune 25 mg soft capsules (ciclosporin) — SmPC §4.4.

Studies and references · 31

  1. S11Mitchnick MA, Fairhurst D, Pinnell SR. Microfine zinc oxide (Z-cote) as a photostable UVA/UVB sunblock agent. J Am Acad Dermatol 1999;40(1):85–90. PMID 9922017.
  2. S12Smijs TG, Pavel S. Titanium dioxide and zinc oxide nanoparticles in sunscreens: focus on their safety and effectiveness. Nanotechnol Sci Appl 2011;4:95-112. PMID 24198489.
  3. S13Kryczyk-Poprawa A, Kwiecień A, Opoka W. Photostability of Topical Agents Applied to the Skin: A Review. Pharmaceutics 2020;12(1):10. PMID 31861803.
  4. S14Gupta M, Mahajan VK, Mehta KS, Chauhan PS. Zinc therapy in dermatology: a review. Dermatol Res Pract 2014:709152. PMID 25120566.
  5. S15Hughes MC, Williams GM, Baker P, Green AC. Sunscreen and prevention of skin aging: a randomized trial. Ann Intern Med 2013;158(11):781-90. PMID 23732711.
  6. S16Licari A, Ruffinazzi G, DE Filippo M, Castagnoli R, Marseglia A, Agostinis F, Puviani M, Milani M, Marseglia GL. A starch, glycyrretinic, zinc oxide and bisabolol based cream in the treatment of chronic mild-to-moderate atopic dermatitis in children. Minerva Pediatr 2017;69(6):470-475. PMID 29181960.
  7. S17Nowicka D, Chilicka K, Dzieńdziora-Urbińska I, Szyguła R. Skincare in Rosacea from the Cosmetologist's Perspective: A Narrative Review. J Clin Med 2023;12(1):115. PMID 36614915.
  8. S18Visser WI, Kannenberg SM, Prevost A, Khoza N, Pillay L, Wiid KJ, Heydenrych IR. Dermocosmetics in Acne Vulgaris: South African Consensus Recommendations With a Focus on Skin of Color. PMID 41689191.
  9. S19Nikolis A, Nestor MS, Czuwara J, Depfenhart M, Fluhr JW, Addor FASA, Piotrowski K, Zielinski Y, Lachmann N, Prygova I, Berlin I, Pellacani G. Concomitant Use of Dermo-Cosmetic Skin Care in Aesthetic Procedures: Systematic Review with Expert Panel Recommendations. Clin Cosmet Investig Dermatol. PMID 41773167.
  10. S20Hanson KM, Clegg RM. Bioconvertible vitamin antioxidants improve sunscreen photoprotection against UV-induced reactive oxygen species. J Cosmet Sci 2003;54(6):589-98. PMID 14730375.
  11. S21Bozzo P, Chua-Gocheco A, Einarson A. Safety of skin care products during pregnancy. Can Fam Physician 2011;57(6):665-7. PMID 21673209 (abstract-only capture).
  12. S22Puaratanaarunkon T, Asawanonda P. A Randomized, Double Blinded, Split-Face Study of the Efficacy of Using a Broad Spectrum Sunscreen with Anti-Inflammatory Agent to Reduce Post Inflammatory Hyperpigmentation After Picosecond Laser. Clin Cosmet Investig Dermatol 2022. PMID 35250287.
  13. S23ASCP, "What To Do Before Waxing, What To Expect & After Care" — qualitative context only per Tier 3 rule.
  14. S30Gupta M et al. Zinc Therapy in Dermatology: A Review. Dermatol Res Pract 2014. PMID 25120566 · PMC4120804.
  15. S31Zhu J et al. Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach. J Control Release 2025;382:113754. PMID 40254135.
  16. S32Titanium dioxide and zinc oxide nanoparticles in sunscreens: focus on their safety and effectiveness. Nanotechnol Sci Appl 2013. PMID 24198489 · PMC3781714 (authors not present in capture).
  17. S33Pirot F et al. In vitro study of percutaneous absorption, cutaneous bioavailability and bioequivalence of zinc and copper from five topical formulations. Skin Pharmacol 1996;9(4):259–69. PMID 8896117.
  18. S34Ahn H-J et al. Zinc penetration through the skin barrier in atopic dermatitis and rosacea using reflectance confocal microscopy. Exp Dermatol 2024;33(1):e14971. PMID 37909707.
  19. S35Recommendations on Periprocedural Skincare for Energy-Based Dermatologic Procedures. Aesthet Surg J Open Forum 2025. PMID 40575009 · PMC12198435 (authors not present in capture).
  20. S36Prevention of Complications in Chemical Peeling. J Cutan Aesthet Surg 2010. PMID 21430836 · PMC3047741 (authors not present in capture).
  21. S37Sobkowska et al. The Role of Cosmetology in an Effective Treatment of Rosacea: A Narrative Review. Clin Cosmet Investig Dermatol 2023. PMID 37303984 · PMC10252991.
  22. S38Skincare in Rosacea from the Cosmetologist's Perspective: A Narrative Review. J Clin Med 2022. PMID 36614915 · PMC9821000 (authors not present in capture).
  23. S40Dermocosmetics in Acne Vulgaris: South African Consensus Recommendations With a Focus on Skin of Color. J Cosmet Dermatol 2026. PMID 41689191 · PMC12905471 (authors not present in capture).
  24. S41Photostability of Topical Agents Applied to the Skin: A Review. Pharmaceutics 2020;12(1):10 (authors not present in capture).
  25. S42CIR, Safety Assessment of Zinc Salts as Used in Cosmetics, Draft Final Report for Panel Review, 9 Feb 2018 — zinc oxide is expressly outside this report's scope; cited only for its statements about zinc oxide's acid reaction chemistry.
  26. S47DermNet — Rosacea.
  27. S48DermNet — Barrier cream.
  28. S49Cangul IT, Gul NY, Topal A, Yilmaz R. Evaluation of the effects of topical tripeptide-copper complex and zinc oxide on open-wound healing in rabbits. Vet Dermatol 2006;17(6):417–23. PMID 17083573 — newly fetched.
  29. S50Inhibitory zinc sites in enzymes. PMID 23456096 · PMC7087665 (authors not present in capture).
  30. S51Size Dependent Uptake and Hemolytic Effect of Zinc Oxide Nanoparticles on Erythrocytes and Biomedical Potential of ZnO-Ferulic acid Conjugates. PMC5482866 (authors not present in capture).
  31. S52Liu H et al. Evidence-based topical treatments (azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid) for acne: an abridged version of a Cochrane systematic review. J Evid Based Med 2020;13(4):275–83. PMID 33034949.

Skin Intelligence is a cosmetic skincare tool, not a medical device, and does not diagnose, treat, cure, or prevent any condition. Always follow the directions on the product you are using — where they differ from anything on this page, the label takes precedence. If you have a skin concern, please see a healthcare professional.

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