What does LHA do?#
LHA (lipohydroxy acid) is a gentle, oil-soluble exfoliant derived from salicylic acid that works gradually to help promote smoother, clearer-looking skin. Its lipophilic nature and slow action make it one of the gentler exfoliating options, well-suited for those who want a milder approach.
- Helps promote smoother, more refined-looking skin texture
- Supports clearer-looking pores with a gentle, gradual approach
- One of the gentler exfoliating options, with a gradual approach to surface exfoliation
How it works
LHA is a lipophilic (oil-loving) exfoliant that gently smooths away dull surface buildup for smoother, brighter-looking skin. Its larger, oil-loving structure means it sinks in more slowly than salicylic acid does, so it works gradually rather than all at once. The result is clearer, more refined-looking skin over time.
How to use LHA#
- It comes in two forms and they belong in different steps — a cleanser at the washing stage, a leave-on serum as a targeted step.
- Ease in gradually, following the frequency on the pack. Daily use is within the usual guidance once your skin is used to it.
- Across the whole area rather than dabbed onto single spots.
- Follow it with a moisturizer. Dryness and a brief sting on application are the things most likely to show up first.
- If it starts to feel tight or drying, use it less often rather than pushing through.
- Stick to one exfoliating product at a time — two on the same skin in the same session is what usually causes the stinging.
- Keep the leave-on to a different evening from retinol, or use the acid in the morning and the retinoid at night, which is how the studies ran it.
This product contains an exfoliating ingredient that may increase your skin's sensitivity to the sun. Discontinue use if irritation occurs and consult a healthcare provider.
Forms you will see it in
LHA exfoliating cleanser
- Where it goes
- Your wash, morning or evening
- How often
- Up to daily
- Strength
- Gentle
- Sun sensitivity
- None
LHA exfoliating serum
- Where it goes
- Before moisturizer, morning or evening
- How often
- Up to daily
- Strength
- Gentle
- Sun sensitivity
- SPF next morning
Using LHA with other ingredients
Pairs well with LHA
Hyaluronic Acid
Works well togetherHyaluronic acid provides hydration that helps offset any dryness from exfoliation.
What not to use with LHA
Azelaic acid
Different timesBoth are active on the skin’s surface and combining them can increase the chance of irritation.
Cysteamine
Different timesThese two are better applied on separate evenings rather than layered together.
Eye-area retinol
Different timesThe eye area is thinner and takes longer to settle, so keep exfoliants to a different evening from your eye retinol.
Other exfoliants
Different timesMore than one exfoliant at once can feel drying, so they’re best kept to separate evenings.
Enzyme Exfoliants · Glycolic Acid (AHA) · Lactic Acid (AHA) · PHA (Polyhydroxy Acid) · Salicylic Acid (BHA)
Retinoids
Different timesRetinoids and exfoliants can both feel drying, so they’re best kept to separate evenings.
Vitamin C
Different timesVitamin C and exfoliants are more comfortable at different times than layered in one routine.
Who should avoid LHA?#
Six situations change whether LHA suits your skin right now. Each one is either a reason to skip it, a reason to go slowly, or nothing to watch for.
- Fragile or Sensitive
- Skip it
- Recent Facial or Laser
- Skip it
- Prone to Redness
- Go slowly
- Dry or Itchy Patches
- Go slowly
- Recent Shave or Wax
- Go slowly
- Maternity & Nursing
- No caution
Prone to Redness — Try it on a small area first, and use it less often — or stop — if you notice stinging or extra redness.
Dry or Itchy Patches — Keep the rest of your routine well moisturized, and use it less often — or stop — if you notice tightness or itching.
Recent Shave or Wax — Avoid for 24 hours after waxing, threading, or dermaplaning.
Cosmetic strength limits for LHA where you live#
| Region | Maximum strength |
|---|---|
| United States | No explicit cap |
| Canada | No explicit cap |
| European Union | No explicit cap |
| Great Britain | No explicit cap |
No cosmetic regulator in these four markets sets a maximum strength for lha. That is a limit on the rules, not a signal to use more: how much goes into a product is the formulator's decision.
Products with LHA#
We may earn a small commission when you buy through these links.
LHA exfoliating cleanser · 4
LHA exfoliating serum · 1
Common questions about LHA#
When should you apply LHA?
- It comes in two forms and they belong in different steps — a cleanser at the washing stage, a leave-on serum as a targeted step.
Which form of LHA should you use?
- LHA exfoliating cleanser — your wash, morning or evening, up to daily. LHA exfoliating serum — before moisturizer, morning or evening, up to daily.
How often can you use LHA?
- Up to daily.
Where do you apply LHA?
- All over the face. Keep it away from your eyes and lips.
Does LHA make skin more sensitive to the sun?
- Only as the LHA exfoliating serum — use sunscreen the next morning. The other form is not flagged.
What should you not use with LHA?
- Space it apart from Azelaic acid, Cysteamine, Eye-area retinol, Other exfoliants, Retinoids and Vitamin C.
Who should avoid LHA?
- Skip it if any of these apply: Fragile or Sensitive and Recent Facial or Laser. Go slowly with Prone to Redness, Dry or Itchy Patches and Recent Shave or Wax.
Is there a cosmetic limit for LHA?
- No. No cosmetic regulator in the United States, Canada, the European Union or Great Britain sets a maximum strength for it. That is a limit on the rules, not a signal to use more.
Related ingredients#
How we check this#
Everything on this page traces to the sources listed below — regulators' own publications and published studies. Where the evidence does not answer a question, it is left unanswered.
Our review is AI-assisted and is not a named expert's opinion. Last reviewed August 6, 2026.
Think something here is out of date or wrong? Email us at wiki@skinintelligence.ai with your reasoning and where you read it. We read what people send, and we update the page when the sources support it.
Regulators and official bodies · 11
- S1Johnson W Jr, Bergfeld WF, Belsito DV, Klaassen CD, Liebler DC, Marks JG Jr, Peterson LA, Shank RC, Slaga TJ, Snyder PW, Fiume M, Heldreth B. Safety Assessment of Capryloyl Salicylic Acid as Used in Cosmetics. Int J Toxicol. 2024 Aug;43(3_suppl):92S–108S. PMID 38465458.
- S16FDA. OTC Monograph M006: Topical Acne Drug Products for Over-the-Counter Human Use. Posted Nov 23 2021 (Final Administrative Order OTC000013).
- S17FDA. Guidance for Industry: Labeling for Topically Applied Cosmetic Products Containing Alpha Hydroxy Acids as Ingredients. January 2005.
- S18FDA. Beta Hydroxy Acids (cosmetic ingredient information page). fda.gov/cosmetics/cosmetic-ingredients/beta-hydroxy-acids.
- S19Health Canada / NNHPD. Acne Therapy monograph. webprod.hc-sc.gc.ca/nhpid-bdipsn.
- S20Health Canada / NNHPD. Anti-Dandruff Products monograph. webprod.hc-sc.gc.ca/nhpid-bdipsn.
- S21Cosmetic Ingredient Review. Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics — Final Amended Report, April 2019. cir-safety.org/sites/default/files/salicy042019FAR.pdf.
- S22Health Canada. Cosmetic Ingredient Hotlist: Prohibited and Restricted Ingredients, 2025 edition.
- S23Commission Regulation (EU) 2019/1966 amending Annexes II, III and V to Regulation (EC) No 1223/2009. EUR-Lex CELEX:32019R1966.
- S25Regulation (EC) No 1223/2009 as retained in UK law. legislation.gov.uk/eur/2009/1223.
- S26UK OPSS Scientific Advisory Group on Chemical Safety. SAG-CS Opinion 05: Salicylic acid restrictions in cosmetic products..
Studies and references · 20
- S2Zeichner JA. The Use of Lipohydroxy Acid in Skin Care and Acne Treatment. J Clin Aesthet Dermatol. 2016 Nov;9(11):40–43. PMID 28210389.
- S3Saint-Léger D, Lévêque JL, Verschoore M. The use of hydroxy acids on the skin: characteristics of C8-lipohydroxy acid. J Cosmet Dermatol. 2007 Mar. PMID 17348998.
- S4Bissonnette R, Bolduc C, Seité S, Nigen S, Provost N, Maari C, Rougier A. Randomized study comparing the efficacy and tolerance of a lipophillic hydroxy acid derivative of salicylic acid and 5% benzoyl peroxide in the treatment of facial acne vulgaris. J Cosmet Dermatol. 2009 Mar. PMID 19250161.
- S5De Cruz R, Nguyen R, Chen P, Kerob D, Gebauer K, Willems A, Tong P, Lee M. From Monotherapy to Adjunctive Therapies: Application of Dermocosmetics in Acne Management Across Australia and New Zealand. Australas J Dermatol. 2025 Jun. PMID 40019045.
- S6Pierard GE, Rougier A. Nudging acne by topical beta-lipohydroxy acid (LHA), a new comedolytic agent. Eur J Dermatol. 2002 Jul-Aug;12(4):XLVII–XLVIII. PMID 12120612.
- S7Li S, He X, Zhang Z, Zhang XS, Niu YG, Steel A, Wang HT. Efficacy and safety of a facial serum and a mask containing salicylic acid and lipohydroxy acid in acne management: A randomized controlled trial. J Cosmet Dermatol. 2023 Sep;22(9):2502–2511. PMID 36999489.
- S8Towersey L, Correia P, Fajgenbaum Feiges M, Euzébio Gonçalves Junior J, Sant'Anna B, Kerob D, Le Floc'h C. Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne. Clin Cosmet Investig Dermatol. 2023. PMID 36698447.
- S9Sitohang IBS, Norawati L, Yenny SW, Kusumawardani A, Murlistyarini S, Setiawan SV, Kekalih A, Riany G, Kerob D. Effectiveness and Safety of a Dermocosmetic Cream as an Adjunct to Adapalene for Mild and Moderate Acne in Indonesia. Clin Cosmet Investig Dermatol. 2024. PMID 39430644.
- S10Bouloc A, Roo E, Imko-Walczuk B, Moga A, Chadoutaud B, Dréno B. A skincare combined with combination of adapalene and benzoyl peroxide provides a significant adjunctive efficacy and local tolerance benefit in adult women with mild acne. J Eur Acad Dermatol Venereol. 2017 Oct. PMID 28573779.
- S11Dal Belo SE, Kanoun-Copy L, Lambert C, Cornillon C, Muller B, Jouni H, Moreau M, Palamarchuk I, Kerob D, Aguilar L. Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris. J Cosmet Dermatol. 2024 Mar. PMID 37941097.
- S12Oresajo C, Yatskayer M, Hansenne I. Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin. J Cosmet Dermatol. 2008 Dec. PMID 19146601.
- S13Chen X, Wang S, Yang M, Li L. Chemical peels for acne vulgaris: a systematic review of randomised controlled trials. BMJ Open. 2018 Apr 28. PMID 29705755.
- S14Bjerring P, Draelos ZD, Fabi SG, Goodman GJ, Hau KC, Haus A, Heydenrych I, Kim J, Lin LC, Sayed K, Sundaram H, Tsubouchi R, Wu Y, Brieva P, Choudhary H, Xiang LF. International Expert Consensus on Integrated Skincare Active Ingredients for Pretreatment and Posttreatment Use With Medical Aesthetic Procedures. J Cosmet Dermatol. 2026 May. PMID 42087526.
- S15Piérard GE, Kligman AM, Stoudemayer T, Lévêque JL. Comparative effects of retinoic acid, glycolic acid and a lipophilic derivative of salicylic acid on photodamaged epidermis. Dermatology. 1999;199(1):50–53. PMID 10449958.
- S24CosmileEurope. Capryloyl Salicylic Acid INCI entry.
- S27Seite S, Rougier A, Talarico S. Randomized study comparing the efficacy and tolerance of a lipohydroxy acid shampoo to a ciclopiroxolamine shampoo in the treatment of scalp seborrheic dermatitis. J Cosmet Dermatol. 2009 Dec. PMID 19958427.
- S28Roberts DW, Aptula AO. Contact allergy to capryloyl salicylic acid: a mechanistic chemistry and structure-activity perspective. Contact Dermatitis. 2015 May;72(5):347–351. PMID 25720316. Commenting on: de Groot A, Rustemeyer T, Hissink D, Bakker M. Contact allergy to capryloyl salicylic acid. Contact Dermatitis. 2014 Sep;71(3):185–187. PMID 25155078. Also: González-Pérez R, Carnero-González L, Martínez-González MI. Allergic Contact Dermatitis Due to Capryloyl Salicylic Acid. Actas Dermosifiliogr. 2016 Oct;107(8):694–695. PMID 27154246.
- S29Draelos ZD, Shalita AR, Thiboutot D, Oresajo C, Yatskayer M, Raab S. A multicenter, double-blind study to evaluate the efficacy and safety of 2 treatments in participants with mild to moderate acne vulgaris. Cutis. 2012 Jun;89(6):287–293. PMID 22838094.
- S30Baumann LS, Oresajo C, Yatskayer M, Dahl A, Figueras K. Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris. J Drugs Dermatol. 2013 Mar. PMID 23545907.
- S31Ly S, Kamal K, Manjaly P, Barbieri JS, Mostaghimi A. Treatment of Acne Vulgaris During Pregnancy and Lactation: A Narrative Review. Dermatol Ther (Heidelb). 2023 Jan. PMID 36447117.








